Several herbal remedies have been used as topical agents to cure burn wound, one of the most common injuries in worldwide. In\nthis study, we investigated the potential use of Cleistocalyx operculatus essential oil to treat the burn wound.We identified a total of\n13 bioactive compounds of essential oil, several of which exhibited the anti-inflammatory and antimicrobial activities. Furthermore,\nthe essential oil showed the antibacterial effect against S. aureus but not with P. aeruginosa. The supportive effect of essential oil\non burn wound healing process also has been proven. Among three groups of mice, wound contraction rate of essential oil treated\ngroup (100%) was significantly higher than tamanu oil treated (79%) and control mice (71%) after 20 days (0.22 �± 0.03 versus\n0.31 �± 0.02 cm2, resp.,
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